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| Product Name | Human Osteopontin Synthetic Peptide |
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| Description | Human Osteopontin Synthetic Peptide. Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D. |
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| Size | 50 ug |
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| Concentration | n/a |
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| Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 6696; Uniprot: P10451 |
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| Catalog # | PEP-1622 |
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| Order / More Info | Human Osteopontin Synthetic Peptide from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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