产品详情 |
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Antigenic Specificity | PSAP |
Clone | 4D5F4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 1:200 - 1:400, Immunocytochemistry: 1:50-1:500, Immunofluorescence: 1:50 - 500, Immunohistochemistry: 1:200 - 1:1000, Western Blot: 1:500 - 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PSAP Monoclonal Antibody (4D5F4). This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in mul |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 5660; Uniprot: P07602 |
Catalog # | MA5-17159 |
Price | |
Order / More Info | PSAP Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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