产品详情 |
Edit |   |
Antigenic Specificity | IL-17A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | ELISA: 0.5-2.0 µg/mL, Functional Assay: 0.93-1.3 µg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 0.25 µg/mL, Western Blot: 0.1-0.2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-17A Polyclonal Antibody. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells to sec |
Immunogen | n/a |
Other Names | CTLA8, IL-17, IL-17A, IL17 |
Gene, Accession # | Entrez: 3605; Uniprot: Q16552 |
Catalog # | PA1-84183 |
Price | |
Order / More Info | IL-17A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|