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| Product Name | Ethyl-L-NIO (hydrochloride) |
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| Description | Purity >95%. Ethyl-L-NIO, the saturated analog of vinyl-L-NIO, is a modestly selective NOS inhibitor. The Ki values for inhibition of nNOS, eNOS, and iNOS by ethyl-L-NIO are 5.3, 18, and 12 µM, respectively, as determined using initial rate measurements. However when evaluating the Ki /Km ratio, ethyl-L-NIO does not show biologically significant selectivity for nNOS over eNOS, and instead favors iNOS (Ki /Km = 3.79, 5, and 0.96 µM, respectively). Although ethyl-L-NIO inhibits nNOS, it does not inactivate nNOS in the presence of NADPH and O2 . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N5 -(1-iminobutyl)-L-ornithine, monohydrochloride, L-N5-(1-Iminobutyl)ornithine hydrochloride |
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| Gene, Accession, CAS # | CAS: 150403-97-7 |
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| Catalog # | LS-H7729 |
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| Price | |
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| Order / More Info | Ethyl-L-NIO (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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