| 产品详情 |
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| Product Name | ETP-46464 |
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| Description | Purity >98% by HPLC. A potent ATR (ATM and Rad3-related) inhibitor (IC50 = 25 nM). It also inhibits the activity of PI3Ka, mTOR and DNA-PKC with IC50's of 170, 0.6 and 36 nM, respectively. ETP-46464 inhibits the restart of stalled replication forks and abrogates S phase arrest after exposure to hydroxyurea. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Methyl-2-(4-(2-oxo-9-(quinolin-3-yl)-2H-[1,3]oxazino[5,4-c]quinolin-1(4H)-yl)phenyl)propanenitrile, ATRi |
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| Gene, Accession, CAS # | CAS: 1345675-02-6 |
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| Catalog # | LS-H3031 |
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| Price | |
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| Order / More Info | ETP-46464 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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