产品名称 Cytochrome P450 2C19 Fluorometric Activity Assay Kit from CREATIVE BIOMART
产品货号 Kit-2124
产品价格 现货询价,电话:010-67529703
产品规格 100 assays
产品品牌 CREATIVE BIOMART
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Product NameCytochrome P450 2C19 Fluorometric Activity Assay Kit
DescriptionCYP2C19 Activity Assay Kit enables rapid measurement of native or recombinant CYP2C19 activity in biological samples such as liver microsomes. The assay utilizes a non-fluorescent CYP2C19 substrate that is converted into a highly fluorescent metabolite detected in the visible range (Ex/Em = 406/468 nm), ensuring a high signal-to-background ratio with little interference by autofluorescence. A highly-selective CYP2C19 inhibitor is provided for determination of CYP2C19 activity in heterogeneous biological samples, where other CYP isozymes may contribute to substrate metabolism. The inhibitor displays greater than 100-fold selectivity for CYP2C19 over other CYPs, ensuring targeted inhibition. CYP2C19 specific activity is calculated by running parallel reactions in the presence and absence of the selective inhibitor and subtracting any residual activity detected with the inhibitor present. The kit contains a complete set of reagents sufficient for performing 50 sets of paired reactions (in the presence and absence of inhibitor).
Size100 assays
Concentrationn/a
ApplicationsRapid assessment of native/recombinant CYP2C19 activity in lysates or microsomal fractions prepared from tissues, cells.Screening of drugs and novel ligands for interaction with native/recombinant CYP2C19.
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Catalog #Kit-2124
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Order / More InfoCytochrome P450 2C19 Fluorometric Activity Assay Kit from CREATIVE BIOMART
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