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| Product Name | SA10 |
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| Description | Purity >95% by NMR. SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5 µM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the Beta-galactosidase activity (IC50 = 11.0 µM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-((Benzo[c][1,2,5]thiadiazole-4-sulfonamido)methyl-N-(3-phenylpropyl)cyclohexanecarboxamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H2748 |
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| Price | |
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| Order / More Info | SA10 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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