| 产品详情 |
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| Product Name | SA9 |
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| Description | Purity >95% by NMR. SA9 inhibits Hh pathway by interacting directly with Smo. It inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 19 µM). Induces the localization of Smo to cilia in ASZ1 cells, but not in IMCD3 cells. Also treatment of Ptch1-/- MEFs with SA9 suppresses the Beta-galactosidase activity (IC50 = 1.0 µM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(3-(4-Fluorophenyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl-N-(3-methylphenethyl)propanamide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H2745 |
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| Price | |
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| Order / More Info | SA9 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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