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| Product Name | Tryptanthrin |
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| Description | Purity >95%. Tryptanthrin is an alkaloid tryptophan derivative originally isolated from various plants and found to have antimicrobial actions. Among its many actions in cells, it inhibits both 5-lipoxygenase and cyclooxygenase-2 (IC50 s = 600 and 64 nM, respectively). Tryptanthrin suppresses angiogenesis in vivo and blocks signaling through VEGFR2 at the level of ERK1/2 signaling in vitro . It also prevents ERK signaling through Nrf2, reducing oxidative stress-induced hepatocytotoxicity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | indolo[2,1-b]quinazoline-6,12-dione, NSC 349447 |
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| Gene, Accession, CAS # | CAS: 13220-57-0 |
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| Catalog # | LS-H10324 |
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| Order / More Info | Tryptanthrin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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