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| Product Name | Xestospongin C |
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| Description | Purity >97% by NMR and TLC. Xestospongin C is a potent and reversible inhibitor of IP3-mediated Ca2+ release, IC50 = 358 nM. Experiments with guinea-pig ileum permeabilized with alpha toxin revealed that Xestospongin C inhibits the IP3 receptor but not the ryanodine receptor in SR membranes. In intact smooth muscle cells it inhibits voltage-dependent Ca2+ and K+ currents at a concentration range similar to that at which it inhibits the IP3 receptor. Xestospongin C is a useful tool for probing the involvement of IP3 receptors in cellular signaling. Cell permeable. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CAS: 88903-69-9 |
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| Catalog # | LS-H14892 |
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| Order / More Info | Xestospongin C from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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