| 产品详情 |
| Edit |   |
|---|
| Product Name | W140 (trifluoroacetate salt) |
|---|
| Description | Purity >95%. Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1 /EDG-1, S1P2 /EDG-5, S1P3 /EDG-3, S1P4 /EDG-6, and S1P5 /EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 µM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate) |
|---|
| Gene, Accession, CAS # | CAS: 909725-64-0 |
|---|
| Catalog # | LS-H10480 |
|---|
| Price | |
|---|
| Order / More Info | W140 (trifluoroacetate salt) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|