| 产品详情 |
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| Antigenic Specificity | ABCB11 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABCB11 Polyclonal Antibody. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
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| Immunogen | n/a |
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| Other Names | ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP, ABC member 16, MDR/TAP subfamily, ATP-binding cassette sub-family B member 11, bile salt export pump, progressive familial intrahepatic cholestasis 2, sister p-glycoprotein |
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| Gene, Accession # | Entrez: 8647; Uniprot: O95342 |
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| Catalog # | PA5-27742 |
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| Price | |
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| Order / More Info | ABCB11 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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