产品详情 |
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Product Name | Limaprost |
Description | Purity >98%. Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is orally active in both rats and guinea pigs at doses of 100 µg/kg as an inhibitor of ADP and collagen induced platelet aggregation. Limaprost is 10-1,000 times more potent than PGE1 as an inhibitor of platelet adhesiveness measured in vitro . Intra-coronary injection (100 ng/kg) or intravenous injection (3 µg/kg) in anesthetized dogs causes vasodilation and increased coronary blood flow by 60-80%. Significant hypotensive effects were seen at 100 and 300 µg/kg orally in rats. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | 11a,15S-dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid, 17Alpha,20-dimethyl-Delta2-PGE1, 17Alpha,20-dimethyl-Delta2-Prostaglandin E1 |
Gene, Accession, CAS # | CAS: 74397-12-9 |
Catalog # | LS-H8477 |
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Order / More Info | Limaprost from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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