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| Product Name | Interferon Regulatory Factor 4, Recombinant, Human, aa144-451 |
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| Description | Chromatographically purified. IRF4 is a transcriptional activator, belonging to the IRF family. It binds to the interferon-stimulated response element (ISRE) of the MHC Class I promoter (but is not induced by Interferons). IRF4 binds the immunoglobulin lambda light chain enhancer, together with Pu.1. It most likely plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. IRF4/MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B cells mainly located in the light zone. Its morphologic spectrum ranged from that of centrocyte to that of a plasmablast/plasma cell, and it displayed a phenotype (MUM1+/Bcl-6/Ki67 ) different from that of most GC B cells (MUM1/Bcl-6+/Ki67+) and mantle B cells (MUM1/Bcl-6 /Ki67). IRF4 is antibody reactive. Source: Recombinant protein corresponding to aa144-451 from human IRF4, expressed in E. coli. Applications: Suitable for use in ELISA, Western Blot and Inhibiton Assays |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | Interferon Regulatory Factor 4, Recombinant, Human, aa144-451 (IRF4, MUM-1, IRF-4, Lymphocyte-specific Interferon Regulatory Factor, LSIRF, NF-EM5, Multiple Myeloma Oncogene 1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209036 |
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| Order / More Info | Interferon Regulatory Factor 4, Recombinant, Human, aa144-451 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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