产品名称 Ferrostatin-1 (Ferrostatin1, Ethyl-3-amino-4-(cyclohexylamino)benzoate) from UNITED STATES BIOLOGICAL
产品货号 217357
产品价格 现货询价,电话:010-67529703
产品规格 25mg
产品品牌 UNITED STATES BIOLOGICAL
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Product NameFerrostatin-1 (Ferrostatin1, Ethyl-3-amino-4-(cyclohexylamino)benzoate)
DescriptionPurity ~99% (HPLC). A cell-permeable 3,4-diaminoethylbenzoate-based antioxidant that effectively prevents Glutamate- (5mM; 3h) induced neurotoxicity in cultured rat OHSC (by 56%, 65%, and 71%, respectively, in CA1, CA3, and Dentrate gyrus; [Fer-1] = 2uM, added 0.5h prior to Glutamate) and Erastin- (50uM; 24h) induced HT-1080 death (EC50 = 60nM) by blocking cytosolic and lipid ROS accumulation (by >80% at 0.5uM in 10uM Erastin-treated HT-1080 cells). Fer-1 does not prevent H2O2- induced necrosis, STS-induced apoptosis, or Iron-independent oxidative death by Rotenone. Solubility: DMSO Primary Target: Free radical scavenger Molar Mass: 262.4
Size25mg
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Catalog #217357
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Order / More InfoFerrostatin-1 (Ferrostatin1, Ethyl-3-amino-4-(cyclohexylamino)benzoate) from UNITED STATES BIOLOGICAL
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