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| Product Name | CD115 Control Peptide (c-fms, Fms, CSF-1R, M-CSFR) |
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| Description | Highly Purified. Synthetic peptide coresponding to aa399-411 (Ser-Leu-Pro-Arg-Leu-Lys-Arg-Ser-Glu-Ser-Gly- Arg-Tyr) (linear) from the extracellular domain of the feline v-fms sequence. Corresponding antibody C2447-52D recognizes c-fms oncoprotein. Species crosseactivity: Human (macrophages and breast tissue) and mouse (macrophages). CD115 is also known as c-fms, marcophage colony stimulating factor receptor, or CSF-1R. It exists in immature (gp130 c-fms) and mature (gp150 c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain. |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2447-52D1 |
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| Order / More Info | CD115 Control Peptide (c-fms, Fms, CSF-1R, M-CSFR) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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