| 产品详情 |
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| Product Name | PI 3,4-K Inhibitor, PIK-93 |
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| Description | Purity ~98% (HPLC). A cell-permeable phenylthiazole compound that acts as a potent, reversible and ATP-competitive PI 3,4-K family selective inhibitor (IC50=16, 19, 39 and 64nM for p110y, PI 4-KIIb, p110a and DNA-PK, respectively). Moderately inhibits p110d, PI 3-KC2b, hsVPS34, ATM, p110b and PI 4-KIIIa (IC50=0.120, 0.140, 0.320, 0.490, 0.590 and 1.1uM, respectively) with minimal inhibition towards a panel of 36-kinases (IC50>10uM). Shown to block ceramide transfer protein-mediated ceramide traffic between endoplasmic reticulum and Golgi in transfected COS-7 cells at 250nM. Formula: C14H16ClN3O4S2 Solubility: DMSO Molecular Weight: 389.9 |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PI 3,4-K Inhibitor, PIK-93 (N-(5-(4-Chloro-3-(((2-hydroxyethyl)amino)sulfonyl)phenyl)-4-methyl-2-thiazolyl)-acetamide) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217657 |
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| Order / More Info | PI 3,4-K Inhibitor, PIK-93 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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