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| Product Name | PI3K, p110 alpha, p55 gamma, Recombinant, Human, His-Tag (Phosphatidylinositol 3-Kinase) |
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| Description | Purified (~70-90%). PI3K (p110alpha/p55gamma) or Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serve as second messengers in growth signaling pathways. PI3K comprises a 110kD catalytic subunit and a regulatory subunit of either 85kD, 55kD, or 50kD. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in the PI3K has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo. PI3K also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses. Source: Recombinant protein corresponding to human PI3K, fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~61kD, 111kD Specific Activity: 14nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_006218 |
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| Catalog # | 500361 |
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| Order / More Info | PI3K, p110 alpha, p55 gamma, Recombinant, Human, His-Tag (Phosphatidylinositol 3-Kinase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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