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| Product Name | Human Wnt-7a Carrier-Free Recombinant Protein |
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| Description | Human Wnt-7a Carrier-Free Recombinant Protein, eBioscience™. Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal. The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade. Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor. Extensive research has shown that deregulation of these pathways or its components can lead to cancer. Human Wnt-1 is encoded as a 370 amino acid precursor that, upon secretion, is cleaved into a 343 amino acid (42 kDa) ma |
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| Size | 15 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent, Neutralization: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 7476; Uniprot: O00755 |
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| Catalog # | 34-8694-166 |
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| Order / More Info | Human Wnt-7a Carrier-Free Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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