| 产品详情 |
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| Product Name | BRD7116 |
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| Description | Purity >98%. BRD7116 is a bis-aryl sufone that acts as a selective inhibitor of leukemia stem cell activity. It exhibits an EC50 value of 200 nM for leukemia stem cells isolated from the bone marrow of leukemic animals in co-culture but does not affect normal hematopoietic stem cells or AML cell lines (EC50 s = 20 µM). Its exact mechanism is not well understood but is thought to involve impairment of the stroma's ability to support leukemia stem cells by inducing transcriptional changes consistent with myeloid differentiation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'-(sulfonyldi-4,1-phenylene)bis [2,2,3,3-tetramethyl-cyclopropanecarboxamide |
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| Gene, Accession, CAS # | CAS: 329059-55-4 |
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| Catalog # | LS-H6890 |
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| Price | |
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| Order / More Info | BRD7116 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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