产品名称 Progranulin, Human, BioAssay™ ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor) from UNITED STATES BIOLOGICAL
产品货号 207352
产品价格 现货询价,电话:010-67529703
产品规格 96 tests
产品品牌 UNITED STATES BIOLOGICAL
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Product NameProgranulin, Human, BioAssay™ ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor)
DescriptionProgranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer`s disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. Sample Type: Cell culture supernatant, plasma, serum Intended Use: The human Progranulin BioAssay™ ELISA Ki
Size96 tests
Concentrationn/a
ApplicationsELISA
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Catalog #207352
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Order / More InfoProgranulin, Human, BioAssay™ ELISA Kit (PEPI, Proepithelin, PC Cell-derived Growth Factor) from UNITED STATES BIOLOGICAL
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