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| Product Name | Progranulin, Recombinant, Human, 593aa, FLAG-Tag |
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| Description | Purity ~90% (HPLC, SDS-PAGE). Progranulin, also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Granulins are a variety of active, 6kD peptides and named granulin A (epithelin 1), granulin B (epithelin 2), granulin C, etc. Both the peptides and intact progranulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Source: Recombinant corresponding to 593aa from human progranulin, fused to FLAG-Tag at C-terminal, expressed in HEK293 cells. Molecular Weight: ~88kD Biological Activity: 1.The effects of phospho-ERK1/2 and non phospho-ERK1/2 by human progranulin-FL |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Progranulin, Recombinant, Human, 593aa, FLAG-Tag (Proepithelin, PEPI, PC Cell-derived Growth Factor) |
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| Gene, Accession, CAS # | SwissProt: P28799 |
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| Catalog # | P9007-34C |
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| Order / More Info | Progranulin, Recombinant, Human, 593aa, FLAG-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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