| 产品详情 |
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| Product Name | Axitinib |
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| Description | Purity >98%. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRBeta (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). Through its effects on VEGFRs, it causes regression of fenestrated, VEGFR-rich capillaries in tumors and normal tissue of mice, which is reversed following removal of the inhibitor. Axitinib has shown promise as a therapeutic in certain cancers and cancer models. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide, AG-013736 |
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| Gene, Accession, CAS # | CAS: 319460-85-0 |
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| Catalog # | LS-H6683 |
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| Price | |
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| Order / More Info | Axitinib from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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