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| Product Name | Necrostatin-1 |
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| Description | Purity >98% by NMR, TLC. Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM). It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM). Necrostatin-1 displays a protective effect in a mouse model of ischemic brain injury, inhibits myocardial cell death and reduces infarct size in various mouse heart models and inhibits glutamate-induced oxytosis in HT-22 cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidazolidinone |
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| Gene, Accession, CAS # | CAS: 4311-88-0 |
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| Catalog # | LS-H14776 |
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| Order / More Info | Necrostatin-1 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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