产品详情 |
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Product Name | CGK 733 |
Description | Originally defined as a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells. Decreases p21CIP1 levels in premature senescent MCF-7 and HCT-116 cells; also exhibits antiproliferative activity in a range of cancer cell lines. Blocks camptothecin-induced p53 phosphorylation and protects cells from camptothecin-induced apoptosis. Purity 98%. MW (observed): 555.84 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | α-Phenyl-N-[2,2,2-trichloro-1-[[[(4-fluoro-3-nitrophenyl)amino]thioxomethyl]amino]ethyl]benzeneacetamide |
Gene, Accession, CAS # | CAS: 905973-89-9 |
Catalog # | 2639/10 |
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Order / More Info | CGK 733 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21680529, 24247150, 26097382 |
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