产品详情 |
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Product Name | DMH2 |
Description | Type I BMP receptor inhibitor (Ki values are <1, 5.4 and 43 nM for ALK6, ALK3 and ALK2, respectively). Exhibits >30-fold selectivity over ALK4, ALK5, BMPR2, AMPK and VEGFR2. Also binds to TGFBR2 (Ki = 85 nM). Decreases growth and induces cell death of H1299 non-small cell lung carcinoma cells in vitro. Enhances liver regeneration in vivo. Purity 98%. MW (observed): 451.52 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline |
Gene, Accession, CAS # | CAS: 1206711-14-9 |
Catalog # | 5580/50 |
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Order / More Info | DMH2 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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