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Product Name | ZM 323881 hydrochloride |
Description | Potent and selective inhibitor of human vascular endothelial growth factor receptor 2 (VEGFR-2/KDR) activity. Selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). Inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). Purity 99%. MW (observed): 411.86 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-((7-Benzyloxyquinazolin-4-yl)amino)-4-fluoro-2-methylphenol hydrochloride |
Gene, Accession, CAS # | CAS: 193000-39-4 |
Catalog # | 2475/10 |
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Order / More Info | ZM 323881 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 20427666, 20625401, 20671228, 21306896, 21423276, 21636859, 25222747, 27616424 |
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