产品详情 |
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Product Name | ZM 449829 |
Description | Potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3) which binds competitively to the JAK3 ATP site. pIC50 values are 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively. Inhibits STAT-5 phosphorylation and T cell proliferation. Purity 98%. MW (observed): 182.22 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-(2-Naphthalenyl)-2-propen-1-one |
Gene, Accession, CAS # | n/a |
Catalog # | 1366/10 |
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Order / More Info | ZM 449829 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 16517948, 18441519, 20395409, 26619345 |
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