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Product Name | Zosuquidar trihydrochloride |
Description | High affinity P-glycoprotein (P-gp) inhibitor (Kd = 79 nM). Restores doxorubicin (Cat. No. 2252) sensitivity in P-gp-expressing multidrug (MDR) resistant cancer cell lines. Also potentiates antitumor efficacy of taxol (Cat. No. 1097) in a MDR human non-small cell lung carcinoma xenograft mouse model. Purity 98%. MW (observed): 636.99 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (αR)-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride. LY 335979 |
Gene, Accession, CAS # | CAS: 167465-36-3 |
Catalog # | 5456/10 |
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Order / More Info | Zosuquidar trihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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