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| Product Name | ZLN 024 hydrochloride |
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| Description | Allosteric AMP-activated protein kinase (AMPK) activator; allosterically stimulates active AMPK heterotrimers, increasing the activity of α1β1γ1 by 1.5-fold and α2β1γ1 by 1.7-fold (EC50 values are 0.42 and 0.95 μM, respectively). Inhibits dephosphorylation of AMPK Thr-172 by PP2Cα. Stimulates glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio. Also decreases fatty acid synthesis and glucose output in primary hepatocytes. Improves glucose tolerance and decreases cholesterol content in db/db mice. Purity 99%. MW (observed): 361.69 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[[2-(2-Bromo-4-methylphenoxy)ethyl]thio]pyrimidine hydrochloride |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 5285/10 |
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| Order / More Info | ZLN 024 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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