产品名称 S-NEPC from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H9957
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameS-NEPC
DescriptionPurity >98%. Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. S-NEPC is a colorimetric substrate used to measure sEH activity. It also is a substrate for Glutathione S-transferase, microsomal epoxide hydrolase and porcine liver carboxylesterase. Hydrolysis of S-NEPC by sEH yields 4-nitrophenol which can be quantified spectrophotometrically at 405 nm. S-NEPC is adaptable for use in 96-well microwell plate readers.
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Other Names4-nitrophenyl-2S,3S-epoxy-3 phenylpropyl carbonate
Gene, Accession, CAS #CAS: 147349-28-8
Catalog #LS-H9957
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Order / More InfoS-NEPC from LIFESPAN BIOSCIENCES INC.
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