| Edit |   |
|---|
| Antigenic Specificity | CHN2 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry: 1:20-1:50 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CHN2 Polyclonal Antibody. This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, enco |
|---|
| Immunogen | n/a |
|---|
| Other Names | OTTHUMP00000202260; beta chimerin; beta-chimaerin; beta-chimerin; rho GTPase-activating protein 3; rho-GTPase-activating protein 3 |
|---|
| Gene, Accession # | Entrez: 1124; Uniprot: P52757 |
|---|
| Catalog # | PA5-53885 |
|---|
| Price | |
|---|
| Order / More Info | CHN2 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|