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Product Name | Phosphoglycerate Kinase Activity Assay Kit (Colorimetric) |
Description | Phosphoglycerate Kinase (PGK1) (EC 2.7.2.3) participates in two of the most important biochemical pathways in living organisms: Glycolysis and Gluconeogenesis. PGK is responsible for the catalysis of the reversible reaction of 1,3-Bisphosphoglycerate (1,3-BPG) and ADP to 3-Phosphoglycerate (3-PG) and ATP. In humans, PGK1 and PGK2, two PGK isozymes, have been characterized. While PGK1 is X-Chromosome-linked variant and expressed in all cells, PGK2 is autosome-linked variant and uniquely expressed in spermatogenic cells. Recent studies have shown deficiency of Phosphoglycerate Kinase could lead to chronic hemolytic anemia, mental disorders and myopathy in humans, whereas PGK overexpression promotes gastric cancer cell invasiveness. Therefore, |
Size | 100 assays |
Concentration | n/a |
Applications | Mechanistic study for cancer development: e.g. Gastric Cancer,Measurement of Phosphoglycerate Kinase (PGK) Activity in various tissues/cells.,Analysis of glycolytic Pathway and Gluconeogenesis Pathway |
Other Names | PGK1,Phosphoglycerate Kinase |
Gene, Accession, CAS # | n/a |
Catalog # | K194-100 |
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Order / More Info | Phosphoglycerate Kinase Activity Assay Kit (Colorimetric) from BIOVISION, INC. |
Product Specific References | n/a |
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