| 产品详情 |
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| Product Name | Human ITGB5 / Integrin Beta 5 Protein (Recombinant) |
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| Description | Purity >95% by SDS-PAGE, MW: 90 kDa. Integrins are a family of cell surface transmembrane receptors, each consisting of an a and a Beta subunit that bind to extracellular matrix (ECM) proteins and cellular counter receptors and associate with the cytoskeleton. In mammals, 24 different integrins are generated through different combinations of 18 a and 8 Beta subunits. A number of human congenital disorders have been associated with defective integrin-mediated adhesion, including the blistering disorder junctional epidermolysis bullosa, the bleeding disorder Glanzmann's thrombastenia , leukocyte adhesion deficiency-I (Beta2 integrins in leukocytes) and leukocyte adhesion deficiency-III, nephrotic syndrome and interstitial lung disease and muscular dystrophy. Integrin alpha-V/beta-5 is a receptor for fibronectin and it recognizes the sequence R-G-D in its ligand. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ITGB5, Integrin Beta 5, Integrin beta-5, Integrin beta-5 subunit, Integrin, beta 5 |
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| Gene, Accession, CAS # | ITGB5, Gene ID: 3693 |
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| Catalog # | LS-G132396 |
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| Order / More Info | Human ITGB5 / Integrin Beta 5 Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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