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Antigenic Specificity | alpha Internexin |
Clone | 2E3 |
Host Species | Mouse |
Reactive Species | human, mouse, rabbit, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: 1 µg/mL, Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry: 1-5 µg/mL, Western Blot: 0.1-0.5 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha Internexin Monoclonal Antibody (2E3). Alpha-internexin (a-internexin) is a type IV intermediate filament originally discovered as it copurified with other neurofilament subunits. On SDS-PAGE gels it runs with an apparent molecular weight of 64 to 66 kDa, with some species variability, although the real molecular weight is about 55kDa; as with the other neurofilament subunits the presence of highly negatively charged sequences results in reduction of SDS-PAGE mobility. A-internexin is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M, and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed only in neurons and in large amounts early in neuronal developmen |
Immunogen | n/a |
Other Names | Alpha-internexin, Alpha-Inx, 66 kDa neurofilament protein, Neurofilament-66, NF-66, NEF5 |
Gene, Accession # | Entrez: 100348512, 226180, 24503, 9118; Uniprot: P23565, P46660, Q16352 |
Catalog # | 32-3600 |
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Order / More Info | alpha Internexin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 16320244, 21084263, 21856723, 22181065, 23338750, 23863343, 24722252, 26096780, 27358064, 28008748 |
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