产品详情 |
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Antigenic Specificity | UBC13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Immunohistochemistry: 2 µg/mL, Western Blot: 0.5-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | UBC13 Polyclonal Antibody. Ubiquitin-conjugating enzyme 13 (Ubc13) was initially discovered in S. cerevisiae as a DNA-damage inducible protein involved in the error-free DNA postreplication repair pathway. It has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. Ubc13 is part of a dimeric ubiquitin-conjugating enzyme complex also containing UEV1A (ubiquitin-conjugating enzyme E2 variant 1) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kin |
Immunogen | n/a |
Other Names | UBC13, UbcH-ben; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; ubiquitin carrier protein N; ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-protein ligase N; yeast UBC13 homolog |
Gene, Accession # | Entrez: 116725, 7334, 93765; Uniprot: P61088, P61089, Q9EQX9 |
Catalog # | PA5-20080 |
Price | |
Order / More Info | UBC13 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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