产品名称 RIP/RIPK1 Antibody from BOSTER BIO
产品货号 PA2051
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificityRIP/RIPK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted: hamster)
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsWB
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DescriptionRabbit IgG polyclonal antibody for Receptor-interacting serine/threonine-protein kinase 1(RIPK1) detection. Tested with WB in Human. No cross reactivity with other proteins. RIPK1(Regulator of G Protein Signaling 3), also called RIP, is an enzyme that in humans is encoded by the RIPK1 gene. Members of the TRAF protein family have been implicated in the activation of NF-kappa-B by the TNF superfamily. By yeast 2-hybrid and coimmunoprecipitation studies using mammalian cell extracts, Hsu et al.(1996) showed that RIP interacts with TRADD, TRAF1, TRAF2, and TRAF3. Hartz(2012) mapped the RIPK1 gene to chromosome 6p25.2 based on an alignment of the RIPK1 sequence with the genomic sequence. Stanger et al.(1995) found that overexpression of Rip in mammalian cells induced morphologic changes characteristic of apoptosis. They suggested that RIP may be an important element in the signal transduction machinery that mediates programmed cell death.
ImmunogenA synthetic peptide corresponding to a sequence in the middle region of human RIP(411-425aa RRRRVSHDPFAQQRP).
Other NamesReceptor-interacting serine/threonine-protein kinase 1;2.7.11.1;Cell death protein RIP;Receptor-interacting protein 1;RIP-1;Serine/threonine-protein kinase RIP;RIPK1;RIP, RIP1;
Gene, Accession #RIPK1, UniProt: Q13546
Catalog #PA2051
Price
Order / More InfoRIP/RIPK1 Antibody from BOSTER BIO
Product Specific Referencesn/a
产品资料