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Product Name | KLK7, 30-253aa, Human, His tag, E.coli (Denatured) |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M uREA, 10% glycerol . KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | kallikrein-7, hK7, PRSS6, SCCE |
Gene, Accession, CAS # | NP 005037 |
Catalog # | ATGP1737 |
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Order / More Info | KLK7, 30-253aa, Human, His tag, E.coli (Denatured) from ATGen |
Product Specific References | n/a |
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