产品名称 KMT5A, 195-352aa, Human, His-tag, Baculovirus from ATGen
产品货号 ATGP3812
产品价格 现货询价,电话:010-67529703
产品规格 250ug, 50ug, 10ug
产品品牌 ATGen
产品概述
产品详情
Edit&nbsp
Product NameKMT5A, 195-352aa, Human, His-tag, Baculovirus
DescriptionPurity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 5mM DTT, 0.2M NaCl, 1mM EDTA, 50% glycerol.. KMT5A, also known as N-lysine methyltransferase KMT5A isoform 1, is an enzyme which catalyzes mono-methylation of histone H4 at lysine 20 (H4K20me1). It is implicated in cell-cycle-dependent transcriptional silencing and mitotic regulation in metazoans. It acts as a barrier to prevent cellular senescence through chromatin-mediated regulation of senescence-associated metabolic remodeling. It mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. The loss of KMT5A concurrently stimulate nucleolar function and retinoblastoma protein-mediated mitochondrial metabolism. Recombinant human KMT5A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size250ug, 50ug, 10ug
Concentrationn/a
ApplicationsSDS-PAGE
Other NamesN-lysine methyltransferase KMT5A isoform 1, KMT5A, PR-Set7, SET07, SET8, SETD8
Gene, Accession, CAS #NP 065115
Catalog #ATGP3812
Price
Order / More InfoKMT5A, 195-352aa, Human, His-tag, Baculovirus from ATGen
Product Specific Referencesn/a
产品资料