产品名称 AIFM1, 98-609aa, Human, His tag, E.coli from ATGen
产品货号 ATGP2598
产品价格 现货询价,电话:010-67529703
产品规格 0.5mg, 100ug, 20ug
产品品牌 ATGen
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Product NameAIFM1, 98-609aa, Human, His tag, E.coli
DescriptionPurity: > 95% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol . Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, also known as AIFM1, is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. AIFM1 has been shown to cause DNA fragmentation and chromatin condensation and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression has been shown to prevent the release of AIFM1 from mitochondria, but not to block its apoptogenic activity. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Recombinant human AIFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size0.5mg, 100ug, 20ug
Concentrationn/a
ApplicationsSDS-PAGE
Other NamesApoptosis-inducing factor 1 mitochondrial isoform 2 precursor, Apoptosis-inducing factor 1, mitochondrial isoform 2 precursor, AIF, CMTX4, COWCK, COXPD6, PDCD8
Gene, Accession, CAS #NP 665811
Catalog #ATGP2598
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Order / More InfoAIFM1, 98-609aa, Human, His tag, E.coli from ATGen
Product Specific Referencesn/a
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