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Product Name | LAMTOR4, 1-99aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT. LAMTOR4 is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Recombinant human LAMTOR4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 100ug, 20ug, 4ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Ragulator complex protein LAMTOR4, C7orf59 |
Gene, Accession, CAS # | NP 001008396 |
Catalog # | ATGP2791 |
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Order / More Info | LAMTOR4, 1-99aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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