产品名称 mab27 Antibody from DENDRITICS SAS
产品货号 DDX0290
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic Specificitymab27
Clonei 127
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgE
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsMACS-separation & FACS
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DescriptionCell surface receptors for the Fc fragments of IgE (FceR) have been identified on a variety of cell types from hematopoietic origin. The low affinity receptor for IgE (CD23) has been described as a B cell-activation marker. IgE-binding factors have been shown to play a major role in the regulation of IgE production. Basophils and mast cells express FceR1, which bind IgE with high affinity and the reaction of allergen with cell-bound IgE induces the release of a variety of pharmacologically active mediators that are responsible for the clinical manifestations of allergic disorders. mAb27 was generated from a mouse immunization program aiming at producing mAb specific for human IgE-Fc in order to map the sites on IgE interacting with receptors on target cells. (Chretien I. et al, J. Immunol, 1988, (9) 141, pp3128-34).
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #DDX0290
Price
Order / More Infomab27 Antibody from DENDRITICS SAS
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