| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | PCH101 |
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| Host Species | Rat |
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| Reactive Species | chimpanzee, cynomolgus monkey, human, nonhuman primate, rhesus monkey |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Frozen): 10 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (PCH101), eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-li |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 102120882, 50943, 574303, 740909; Uniprot: Q9BZS1 |
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| Catalog # | 14-4776-80 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16177055, 16304057, 16540683, 16728694, 17166272, 17182968, 17218989, 17449799, 17452519, 17641056, 17878392, 18057064, 18413770, 18430198, 18566447, 18567616, 18684941, 18820132, 18941119, 19147574, 19208751, 19255331, 19494275, 19535642, 19641184, 19654865, 19661482, 19801510, 19825957, 19845018, 19996091, 20053772, 20194631, 20617900, 20727190, 20849552, 21062439, 21148332, 21179201, 21273544, 21423069, 21533107, 21715501, 21856934, 21864372, 21917155, 21927947, 21989987, 22130163, 22207629, 22261031, 22300641, 22442246, 22533972, 22545138, 22556091, 22569001, 22912740, 22943196, 22977558, 22998457, 23162126, 23170257, 23297127, 23382115, 23419694, 23552371, 23625925, 23683514, 23712790, 23950176, 24044963, 24150258, 24231351, 24244265, 24317395, 24696233, 24771328, 24879794, 24903021, 24960164, 24990119, 25050704, 25071071, 25200768, 25320361, 25329329, 25359003, 25385798, 25432519, 25924895, 26190648, 26414764, 26415669, 26451301, 26740106, 26799288, 26844452, 26903606, 27182555, 27284313, 27286889, 27482882, 28027623, 28092916, 28176332, 28290464, 28389590, 28439450, 28567040, 29371976, 29386580 |
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