| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | PCH101 |
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| Host Species | Rat |
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| Reactive Species | chimpanzee, cynomolgus monkey, human, nonhuman primate, rhesus monkey |
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| Isotype | IgG2a, kappa |
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| Format | Alexa Fluor 488 conjugate |
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| Size | 100 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (PCH101), Alexa Fluor 488, eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 102120882, 50943, 574303, 740909; Uniprot: Q9BZS1 |
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| Catalog # | 53-4776-42 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16177055, 16304057, 16728694, 19005268, 19435913, 19494275, 19845018, 20617900, 20877632, 21138560, 21179201, 21273544, 21715555, 22130163, 22442246, 22556091, 22943196, 23223361, 23676463, 23712790, 23776439, 23799890, 23818845, 24044963, 24051380, 24231351, 24373350, 24737144, 25432519, 25949860, 25984539, 26414764, 26415669, 26451301, 26476407, 26740106, 26903606, 27284313, 28290464, 29371976, 29386580 |
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