| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | FOXP3 |
|---|
| Clone | PCH101 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | chimpanzee, cynomolgus monkey, human, nonhuman primate, rhesus monkey |
|---|
| Isotype | IgG2a, kappa |
|---|
| Format | allophycocyanin (APC) conjugate |
|---|
| Size | 100 Tests |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 5 µL (0.5 µg)/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | FOXP3 Monoclonal Antibody (PCH101), APC, eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, |
|---|
| Immunogen | n/a |
|---|
| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
|---|
| Gene, Accession # | Entrez: 102120882, 50943, 574303, 740909; Uniprot: Q9BZS1 |
|---|
| Catalog # | 17-4776-42 |
|---|
| Price | |
|---|
| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 16177055, 16304057, 16537805, 16728694, 16917003, 17196245, 17414320, 17545278, 17898053, 17959847, 18250226, 18270368, 18430785, 18497876, 18519750, 18820132, 18924611, 19034017, 19147574, 19321758, 19494275, 19843932, 20127724, 20174666, 20302964, 20371478, 20389017, 20644160, 20799941, 20921523, 21179201, 21211658, 21242295, 21273544, 21347311, 21450832, 21708033, 21799877, 21900196, 21904560, 22129252, 22210907, 22322668, 22383993, 22544928, 22581007, 22585585, 22829946, 22943196, 23029309, 23129754, 23144765, 23145169, 23244635, 23478407, 23696918, 23842750, 24044963, 24090653, 24143230, 24236187, 24498387, 24633313, 24822053, 24876970, 24918929, 25320361, 25418634, 25495598, 25531831, 25996472, 26032202, 26155415, 26276872, 26291831, 26376720, 26414764, 26415669, 26451301, 26451304, 26512654, 26513368, 26740106, 26842680, 26903606, 27057444, 27284313, 27553411, 27565342, 28176332, 28290464, 28615202, 29371976, 29386580 |
|---|
| 产品资料 |
|
|