| 产品详情 |
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| Antigenic Specificity | FOXP3 |
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| Clone | PCH101 |
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| Host Species | Rat |
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| Reactive Species | chimpanzee, cynomolgus monkey, human, nonhuman primate, rhesus monkey |
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| Isotype | IgG2a, kappa |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 25 Tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 5 µL (0.25 µg)/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FOXP3 Monoclonal Antibody (PCH101), PE, eBioscience™. FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, |
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| Immunogen | n/a |
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| Other Names | AIID, DIETER, Forkhead box P3, foxp3, IPEX, JM2, PIDX, SCURFIN, XPID |
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| Gene, Accession # | Entrez: 102120882, 50943, 574303, 740909; Uniprot: Q9BZS1 |
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| Catalog # | 12-4776-41 |
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| Price | |
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| Order / More Info | FOXP3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 16177055, 16304057, 16503495, 16514056, 16645171, 16728694, 16917003, 17062729, 17200409, 17644734, 17688698, 17921346, 18162042, 18502823, 18550794, 18815628, 18980970, 19050306, 19118070, 19201865, 19229054, 19277040, 19321758, 19343213, 19494275, 19597336, 19841178, 19845018, 20018909, 20068105, 20113470, 20126379, 20164417, 20363971, 20424188, 20733946, 20798236, 20842106, 20921939, 21179201, 21273544, 21283755, 21304824, 21471231, 21513715, 21677143, 21850024, 21934066, 21943647, 22101351, 22112244, 22159143, 22162758, 22235276, 22369276, 22396788, 22442246, 22451717, 22466343, 22490441, 22690128, 22943196, 23559897, 23686488, 23776439, 23878315, 24044963, 24270546, 24331831, 24498287, 24498387, 24528482, 24637664, 24947606, 25729646, 25806780, 26116238, 26122357, 26182204, 26284362, 26291831, 26414764, 26415669, 26529008, 26740106, 26770214, 26844452, 26885861, 26903606, 27086659, 27141331, 27195118, 27211045, 27217956, 27284313, 27626702, 27703517, 28092916, 28290464, 28469075, 28808483, 29371976, 29386580, 29576375 |
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