产品详情 |
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Antigenic Specificity | DOK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DOK1 Polyclonal Antibody. Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok. |
Immunogen | n/a |
Other Names | TLP1, TP1, TROVE1, VAULT2, p240; TROVE domain family, member 1; p80 telomerase homolog; telomerase protein 1; telomerase protein component 1 |
Gene, Accession # | Entrez: 1796; Uniprot: Q99704 |
Catalog # | PA5-19860 |
Price | |
Order / More Info | DOK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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