| 产品详情 |
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| Antigenic Specificity | c-Myc |
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| Clone | 9E10 |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgG1 |
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| Format | peroxidase (HRP) conjugate |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Direct-Blot™ HRP anti-c-Myc. The c-myc protein is a 62 kD nuclear factor that is ubiquitously expressed in the nucleus. c-myc is part of a heterodimeric complex with MAX that acts as a potent transcriptional activator. c-myc is modified by glycosylation and phosphorylation and has been shown to interact with a number of proteins including SMAD2, SMAD3, Pam, cdc6, BRCA1, Mlh1, p34cdc2, MAD, and Sp1. c-myc is extremely labile and is degraded very quickly even in extracts prepared with boiling SDS sample buffer, such that the observed protein size is approximately 41 kD. The 9E10 monoclonal antibody recognizes human myc and the 10 amino acid epitope tag of human c-myc. The 9E10 antibody has been shown to be useful in a number of applications including Western blotting, direct ELISA, flow cytometry, immunoprecipitation, immunofluorescence, immunohistochemistry (paraffin), and immunoaffinity purification of proteins expressing the human c-myc tag. |
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| Immunogen | Amino acids 408-439, C-terminal region of human c-myc |
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| Other Names | Oncogene Myc, Myc proto-oncogene protein |
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| Gene, Accession # | Gene ID: 4609 |
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| Catalog # | 626803 |
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| Price | |
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| Order / More Info | c-Myc Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21849440,22407129,22508929,22918893,23319653,23467000,23761676,24344237,25994292 |
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