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Product Name | MAPK10, 1-464aa, Human, His-tag, Baculovirus |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT, 0.1mM PMSF. MAPK10, also known as mitogen-activated protein kinase 10, is a member of the MAP kinase family. This group of protein kinases includes at least 10 members that interact selectively with ATF2, Jun and Elk-i transcription factors. It acts as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Also, expression of multiple JNK isoforms provides a mechanism for the generation of tissue-specific responses to the activation of the JNK signal transduction pathway. Recombinant human MAPK10, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Mitogen-activated protein kinase 10, MAPK10, JNK3, JNK3A, p493F12, p54bSAPK, PRKM10, SAPK1b |
Gene, Accession, CAS # | NP 620448 |
Catalog # | ATGP3837 |
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Order / More Info | MAPK10, 1-464aa, Human, His-tag, Baculovirus from ATGen |
Product Specific References | n/a |
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