| 产品详情 |
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| Product Name | N,N'-Dicyclohexylurea |
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| Description | Purity >98%. Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (sEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). N,N' Dicyclohexylurea (DCU) is a selective sEH inhibitor with IC50 values of 160 and 90 nM for recombinant human and mouse sEH, respectively. At 10 µM, DCU blocks the hydrolysis of cis - and trans-EETs by rat red blood cells and porcine coronary endothelial cells as well as completely inhibits 14,(15)-EET-induced PPARAlpha activation. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'-dicyclohexyl-urea, DCU, NSC 17013 |
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| Gene, Accession, CAS # | CAS: 2387-23-7 |
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| Catalog # | LS-H8866 |
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| Order / More Info | N,N'-Dicyclohexylurea from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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